Development of 'DFG-out' inhibitors of gatekeeper mutant kinasesHWAN GEUN CHOI; JIANMING ZHANG; WEISBERG, Ellen et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 16, pp 5297-5302, issn 0960-894X, 6 p.Article

Design and synthesis of a potential SH2 domain inhibitor bearing a stereodiversified 1,4-cis-enediol scaffoldMARIAN, Christine; RONG HUANG; BORCH, Richard F et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 52, issn 0040-4020, 10057, 10216-10221 [7 p.]Article

Design, synthesis and biological evaluation of novel acrylamide analogues as inhibitors of BCR―ABL kinaseSHUXIN LI; ZHENGLIN YAO; YANJIN ZHAO et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 16, pp 5279-5282, issn 0960-894X, 4 p.Article

Pyrazine-based Syk kinase inhibitorsFORNS, Pilar; ESTEVE, Cristina; VIDAL, Bernat et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 8, pp 2784-2788, issn 0960-894X, 5 p.Article

2,7-Pyrrolo[2,1-n[1,2,4]triazines as JAK2 inhibitors: Modification of target structure to minimize reactive metabolite formationWEINBERG, Linda R; ALBOM, Mark S; UNDERINER, Ted L et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 24, pp 7325-7330, issn 0960-894X, 6 p.Article

Novel Patented Src Kinase InhibitorLU, Xiao-Ling; LIU, Xiao-Yu; XIN CAO et al.Current medicinal chemistry. 2012, Vol 19, Num 12, pp 1821-1829, issn 0929-8673, 9 p.Article

Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agentsYANG, Xian-Hui; LU XIANG; XI LI et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 9, pp 2789-2795, issn 0968-0896, 7 p.Article

HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY WITH ULTRAVIOLET DETECTION AND PROTEIN PRECIPITATION AS A WAY OF QUANTITATIVE DETERMINATION OF NILOTINIB WITH AND WITHOUT INTERNAL STANDARDDZIADOSZ, Marek; WAGNER, Marie-Christine; LIPKA, Daniel B et al.Journal of liquid chromatography & related technologies. 2012, Vol 35, Num 17-20, pp 2503-2510, issn 1082-6076, 8 p.Article

Role of the Hypoxic Microenvironment in the Antitumor Activity of Tyrosine Kinase Inhibitors : Protein kinases in cancer: recent findingsFILIPPI, I; NALDINI, A; CARRARO, F et al.Current medicinal chemistry. 2011, Vol 18, Num 19, pp 2885-2892, issn 0929-8673, 8 p.Article

Using the TOPS-MODE approach to fit multi-target QSAR models for tyrosine kinases inhibitorsMARZARO, Giovanni; CHILIN, Adriana; GUIOTTO, Adriano et al.European journal of medicinal chemistry. 2011, Vol 46, Num 6, pp 2185-2192, issn 0223-5234, 8 p.Article

A Structure-Function Perspective of Jak2 Mutations and Implications for Alternate Drug Design Strategies: The Road not TakenGNANASAMBANDAN, K; SAYESKI, P. P.Current medicinal chemistry. 2011, Vol 18, Num 30, pp 4659-4673, issn 0929-8673, 15 p.Article

Design of two new chemotypes for inhibiting the Janus kinase 2 by scaffold morphingFURET, Pascal; GERSPACHER, Marc; PISSOT-SOLDERMANN, Carole et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 6, pp 1858-1860, issn 0960-894X, 3 p.Article

Recent Progress of Src SH2 and SH3 Inhibitors as Anticancer AgentsLU, X.-L; CAO, X; LIU, X.-Y et al.Current medicinal chemistry. 2010, Vol 17, Num 12, pp 1117-1124, issn 0929-8673, 8 p.Article

Structural basis for the inhibitor recognition of human Lyn kinase domainMIYANO, Nao; KINOSHITA, Takayoshi; NAKAI, Ryoko et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 23, pp 6557-6560, issn 0960-894X, 4 p.Article

Preparation of Heteroaryloxetanes and Heteroarylazetidines by Use of a Minisci ReactionDUNCTON, Matthew A. J; ESTIARTE, M. Angels; JOHNSON, Russell J et al.Journal of organic chemistry. 2009, Vol 74, Num 16, pp 6354-6357, issn 0022-3263, 4 p.Article

Synthesis and optimization of substituted furo[2,3-d]-pyrimidin-4-amines and 7H-pyrrolo[2,3-d]pyrimidin-4-amines as ACK1 inhibitorsXIANYUN JIAO; KOPECKY, David J; FARRELLY, Ellyn et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 19, pp 6212-6217, issn 0960-894X, 6 p.Article

Hybrid compounds as new Bcr/Abl inhibitorsDEPINGWANG; ZHANG ZHANG; ZHENGCHAO TU et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 7, pp 1965-1968, issn 0960-894X, 4 p.Article

Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cellsRADI, Marco; BRULLO, Chiara; PAGANO, Dafne et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 19, pp 5928-5933, issn 0960-894X, 6 p.Article

Synthesis of 3-phenylpyrazolopyrimidine-1,2,3-triazole conjugates and evaluation of their Src kinase inhibitory and anticancer activitiesKUMAR, Anil; AHMAD, Israr; CHHIKARA, Bhupender S et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 5, pp 1342-1346, issn 0960-894X, 5 p.Article

O-Aryl α,β-D-ribofuranosides: Synthesis & highly efficient biocatalytic separation of anomers and evaluation of their Src kinase inhibitory activitySHARMA, Raman K; SINGH, Sukhdev; TIWARI, Rakesh et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 23, pp 6821-6830, issn 0968-0896, 10 p.Article

Recent Developments in the Third Generation Inhibitors of Bcr-AbI for Overriding T315I MutationLU, X. Y; CAI, Q; DING, K et al.Current medicinal chemistry. 2011, Vol 18, Num 14, pp 2146-2157, issn 0929-8673, 12 p.Article

Synthesis and docking study of 2-phenylaminopyrimidine Abl tyrosine kinase inhibitorsSHUANG LÜ; QUN LUO; XIANG HAO et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 23, pp 6964-6968, issn 0960-894X, 5 p.Article

AG490 Promotes HIF-1α Accumulation by Inhibiting Its HydroxylationFERNANDEZ-SANCHEZ, R; BERZAL, S; ORTIZ, A et al.Current medicinal chemistry. 2012, Vol 19, Num 23, pp 4014-4023, issn 0929-8673, 10 p.Article

In vitro and in vivo evaluation of 6-aminopyrazolyl-pyridine-3-carbonitriles as JAK2 kinase inhibitorsTAO WANG; IOANNIDIS, Stephanos; BEBERNITZ, Geraldine et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 10, pp 2958-2961, issn 0960-894X, 4 p.Article

Protein kinase affinity reagents based on a 5-aminoindazole scaffoldKRISHNAMURTY, Ratika; BROCK, Amanda M; MALY, Dustin J et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 1, pp 550-554, issn 0960-894X, 5 p.Article